Medical Breakthrough: US, Netherlands and India researchers report the first gene mutation tied to pyoderma gangrenosum, with a TNF inhibitor helping at least one patient reach remission. EU Health Tech: Azalea Vision enrolls the first patient in a proof-of-concept study of a smart contact lens aimed at keratoconus and presbyopia, run at a Dutch clinic and Belgium’s UZA. Rail Disruption: Eurostar delays are cascading across Belgium, France, Germany and the Netherlands as live track and station issues stack with planned engineering work, with compensation tied to whether delays hit 60 minutes. Aviation & Industry: Aviation Week’s MRO Europe returns to Amsterdam Oct 27–29, spotlighting AI-enabled maintenance and greener operations with 600+ exhibitors. Space & Satellites: Sidus Space shifts LizzieSat-5 to SpaceX’s Bandwagon-6, targeting no earlier than April 2027 after expanded qualification testing. Cybersecurity: CISA adds Citrix NetScaler flaws to its Known Exploited Vulnerabilities catalog after reports of global zero-day exploitation. Energy Transition: Heat pump sales surge across Europe as electricity taxes fall and oil-and-gas prices rise, with policy changes pushing electrification. Data Infrastructure: EMEA data centre capacity tops 12GW, while power access increasingly determines which AI projects can actually get built. Climate Data Rescue: Digitisation of Aruba, Curaçao and Sint Maarten meteorological archives completes, preserving long-term records for better climate projections. Tech Policy & Kids: The EU’s KIDS Act proposal would restrict social media access for children under 13 and limit features for ages 13–15.